Search results for "Dried blood"
showing 5 items of 5 documents
Using VIS/NIR and IR spectral cameras for detecting and separating crime scene details
2012
Detecting invisible details and separating mixed evidence is critical for forensic inspection. If this can be done reliably and fast at the crime scene, irrelevant objects do not require further examination at the laboratory. This will speed up the inspection process and release resources for other critical tasks. This article reports on tests which have been carried out at the University of Jyväskylä in Finland together with the Central Finland Police Department and the National Bureau of Investigation for detecting and separating forensic details with hyperspectral technology. In the tests evidence was sought after at an assumed violent burglary scene with the use of VTT's 500-900 nm wave…
Dried blood spots: challenges
2013
Severe reduction of blood lysosomal acid lipase activity in cryptogenic cirrhosis: A nationwide multicentre cohort study
2017
Background and aims Blood lysosomal acid lipase (LAL) is reduced in non-alcoholic steatohepatitis, which is the major cause of cryptogenic cirrhosis (CC); few data on LAL activity in CC do exist. We investigated LAL activity in a cohort of patients with liver cirrhosis. Methods This is a multicentre cohort study including 274 patients with liver cirrhosis of different aetiology from 19 centres of Internal Medicine, Gastroenterology and Hepatology distributed throughout Italy. Blood LAL activity (nmol/spot/h) was measured with dried blood spot extracts using Lalistat 2. Results Overall, 133 patients had CC, and 141 patients had cirrhosis by other causes (61 viral, 53 alcoholic, 20 alcoholic …
Large-scale screening of lipase acid deficiency in at risk population
2021
International audience; BACKGROUND: Lysosomal acid lipase deficiency (LALD, OMIM#278000) is a rare lysosomal disorder with an autosomal recessive inheritance. The main clinical manifestations are related to a progressive accumulation of cholesteryl esters, triglycerides or both within the lysosome in different organs such as the liver, spleen, and cardiovascular system. A wide range of clinical severity is associated with LALD including a severe very rare antenatal/neonatal/infantile phenotype named Wolman disease and a late-onset form named cholesteryl ester storage disease (CESD). METHODS: This study aimed to investigate a cohort of at-risk patients (4174) presenting with clinical or biol…